ISSN 25226592
DOI：10.6763/IJTCMHP
1.
抗微生物製劑的抗藥性問題，一直都是公共衛生上被關注的議題，甚至於COVID-19抗微生物製劑的抗藥性問題，一直都是公共衛生上被關注的議題，甚至於COVID-19(Coronavirus Disease-2019)疫情爆發更是如此。面對抗藥性問題，可從藥物開發以提供解方。本研究從本土芸香預防保健的豐富性來擴展實際應用，以指標成分肉桂芸香鹼(harmine)為基礎，搭配卵轉鐵蛋白(ovotransferrin，OTRF)作為加成劑，測試其複方的抗微生物活性。除收集臨床抗藥性菌株進行複方抑菌測試外，復以有禽類冠狀病毒(Avian coronavirus, AvCoV)之稱的傳染性支氣管炎病毒(infectious bronchitis virus, IBV)作為標的，觀測其改善病毒感染後胚蛋病變及存活情形。本研究使用傳染性支氣管炎病毒減毒疫苗IB 4-91 作為起始病毒株，接種於胚蛋二輪後收集尿囊(allantoic)液以取得活化病毒。本產芸香萃取之肉桂芸香鹼在搭配卵轉鐵蛋白之下，對呼吸道分離的臨床菌株，不論是對格蘭氏陰性或是陽性菌皆具協同性的抑菌活性。對於病毒而言，活化後的傳染性支氣管炎病毒，較原始疫苗病毒株有更強之感染性與毒性，縮短了胚胎死亡時間；以複方處理後，可減少雞胚的病毒異常毒化情形，並且將存活率由33%提升至66~100%。以本產芸香萃取出的肉桂芸香鹼為主體，搭配卵轉鐵蛋白設計成複方，不僅具協同性作用，可抑制抗藥性臨床菌株，同時亦可抑制傳染性支氣管病毒，此廣效之抗微生物的效果，具有開發成外用消毒或治療藥物的潛力。
關鍵字：本產芸香、肉桂芸香鹼、抗微生物6
- 2.
- 運用正交試驗設計法優化無溶劑微波萃取玫瑰純露實驗參數之研究
- Study on Optimization of Experimental ParametersStudy on Optimization of Experimental Parametersfor Solvent-Free Microwave Extraction of Rose Hydrosol byOrthogonal Test Design Method
- 歐明秋*Ou, Ming-Chiu* / 侯佩恩Hau, Pei-En
- 摘要
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本研究選用南台灣農場栽種的玫瑰花瓣進行無溶劑微波萃取純露，運用正交試驗L9(34)本研究選用南台灣農場栽種的玫瑰花瓣進行無溶劑微波萃取純露，運用正交試驗L9(34)設計針對影響萃取的四項變因：玫瑰採收後天數、萃取時間、玫瑰花瓣重量及萃取功率進行優選參數研究。試驗結果顯示，影響純露萃取率的重要程度排序為萃取時間 > 萃取功率 > 玫瑰花瓣重量 > 玫瑰採收後天數，藉由變異數分析確認影響純露萃取率之顯著變因為時間與瓦數。為確保微波萃取玫瑰純露品質，並以DPPH 自由基清除率為評選依據，影響清除率的重要程度排序為玫瑰花瓣重量 > 萃取時間 > 萃取功率 > 玫瑰採收後天數，其中玫瑰花瓣重量為顯著變因；優選結果建議採收後第三天玫瑰花瓣重量200 g，萃取時間25 min、功率500 W為最佳參數，兼顧質與量雙重考量，本研究建議該參數為無溶劑微波萃取玫瑰花瓣之最優選結果。經氣相層析質譜儀分析結果顯示，微波萃取玫瑰純露含苯乙醇、香葉醇、香茅醇與橙花醇四種成分加總比例高達82.22%，而蒸餾萃取之純露加總比例僅25.10%，顯示微波萃取優於蒸餾萃取，其香氣濃郁程度亦較佳。結論無溶劑微波萃取玫瑰純露不僅能大幅縮短萃取時間，更可獲取高比例醇類香氣成分，提升清除自由基能力，實驗條件參數亦可做為未來微波萃取玫瑰純露之參考依據。
關鍵字：正交法、微波萃取、玫瑰、純露、清除自由基
AbstractRose petals grown on farms in southern Taiwan were used for solvent-free microwave extractionRose petals grown on farms in southern Taiwan were used for solvent-free microwave extractionof hydrosol, and orthogonal test L9(34) design four variables: days after rose harvest, extraction time,rose petal weight and extraction power was used to study the optimal parameters that affect extraction.The order of importance for influencing extracting yield of hydrosol is extraction time > extractionpower > rose petal weight > days after rose harvest. It was confirmed by variance analysis thatextraction time and extraction power significantly influence the extracting yield of hydrosol. Ensurethe quality of rose hydrosol extracted by microwave, the optimization is based on the DPPH freeradical scavenging rate. The order of importance for the scavenging rate is rose petal weight >extraction time > extraction power > days after rose harvest, where rose petal weight is a significantfactor. The optimal results suggest that the weight of rose petals on the third day after harvesting is200 g, the extraction time is 25 min, and the power is 500 W were as the best parameters formicrowave extraction. Basing both quality and quantity requirement, our study suggests that this isthe best result for solvent-free microwave extraction of rose petals. The total proportion of fouralcohol components, i.e. phenylethyl alcohol, geraniol, citronellol and nerol, was 82.22% by gaschromatography-mass spectrometry analysis. The total proportion of the same components indistillation extraction is only 25.10%, which shows that microwave extraction is better thandistillation extraction, and its aroma is also better. Conclusion solvent-free microwave extraction ofrose hydrosol can not only greatly shorten the extraction time, but also obtain a high proportion ofalcohol aroma components and improve the ability to scavenge free radicals. The experimentalparameters can also be used as a reference for future microwave extraction of rose hydrosol.Keywords: orthogonal test design, microwave extraction, rose, hydrosol, free radicalscavenging.
- 3.
- 飼糧中添加山藥複方降低斷乳仔豬死亡率之影響研究
- Study on The Effect of Adding Common Yam Compound in Diet to Reduce The Mortality of Weaned Piglets
- 林文宏*Lin, Wen-Hung / 王献銘Wang, Hsien-Ming / 王韋棠
- 4.
- 中医本草主题背景下文创产品的设计原则及优化创新
- Design Principles and Optimization for Cultural and Creative Products in Chinese Herbal Medicine Context
- 周文文* Zhou Wenwen / 叶茂 Ye Mao
- 5.
- 复方精油按摩结合艾灸减小腹部围度的效果观察
- Observation on The Effect of Compound Essential Oil Massage Combined with Moxibustion on Reducing Abdominal Circumference
- 闵茹Min Ru
- 6.
- 食材溯源之田間管理個案研究 - 以落葵施用不同有機肥料之效益分析
- A Case Study on The Field Management of Food Traceability - Benefit Analysis of Using Different Organic Fertilizers on
- The Basella alba Linn.
- 林文宏* Lin, Wen-Hung
- 摘要
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睡眠的时长直接影响着人体的代谢功能，特别是男性老年人，受睡眠质量的影响最大[ ]， 缺乏深度睡眠、长时间睡眠的群体在白天的精神较差，容易产生疲惫感，因此引发其他的身体 疾病；睡眠时间不足的状态长时间维持的话，个人的情绪更加消沉，容易产生负面想法。相关 研究也证明芳香类中药可以通过嗅觉通路达到镇静、安神等功效，或可成为改善老年人睡眠障 碍的新途径，在睡眠障碍的治疗领域必将具有广阔的前景。
关键词 芳香疗法，老年人，睡眠障碍，研究进展
AbstractThe length of sleep directly affects the metabolic function of the human body, especially the male elderly, which is most affected by the quality of sleep []. The group lacking deep sleep and long-term sleep has poor spirit during the day and is prone to fatigue, which leads to other physical diseases; If the state of insufficient sleep time is maintained for a long time, personal mood is more depressed and prone to negative thoughts. Relevant studies have also proved that aromatic traditional Chinese medicine can achieve sedative and calming effects through the olfactory pathway, or can become a new way to improve sleep disorders in the elderly. It will have broad prospects in the treatment of sleep disorders..
Keywords: Aromatherapy, Aged, Sleep disorders, Research & Progress
譚彩鳳Tang, Tsai-Fong
摘要
根據勞工保險局統計發現，肌肉骨骼酸痛發生率由 2000 年的 58%，提升至 2010 年的 85% （勞委會勞工安全衛生研究所，2014），國外調查發現機構老人慢性疼痛比率 48.5~79%(Won et al.,2004)，台灣老人慢性疼痛比率在社區方面為 42%，機構則為 43.1~65.3%(Tsarist al.,2004； Tsai et al.,2005) ，當中頭皮、關節炎引起的疼痛、僵硬與腫脹，更是許多老人長期慢性酸痛 的主因，常會影響頭、膝、髖、肩及手指等關節(Lansbury,2000)，當手部或手臂關節酸痛，就 會引起活動功能受限，無法執行日常生活(Miller & Reynolds,2012)，所以處理高齡者頭皮紓 壓、痠痛問題十分重要。 芳香精油主要是植物將其本身光合作用所產生的養份轉化成芳香分子進而利用精油萃 取出植物的精華，是大自然給人類最寶貴的禮物。利用精油天然植物菁華滾珠瓶來促進身心 健康，透過皮膚、經絡到神經系統、荷爾蒙系統、血液系統、免疫系統，幫助人體身心舒解、 調理新陳代謝，達到促進身體健康、心理愉悅的功能。解決銀髮族源於工作生活與生活壓力 所形成之內在情緒失調所造成的頭皮、肌肉與健康問題。 本研究實驗目的以白檀香、羅勒、絲柏、迷迭香、快樂鼠尾草、薄荷等精油配合甜杏仁 油作滾珠瓶、刮痧按摩，採用類實驗法，採隨機取樣，樣本來自基隆 12 位已達 50 到 65 歲人 員，有上班之銀髮族為主。其對象有醫療人員，教職員工，一般高齡老人，預計做頭皮芳香 紓壓及擴香吸嗅，時間為期八週進行芳香精油滾珠瓶介入刮痧按摩，提升日常生活及環境免 疫之防護。實驗前，受測者先進行 3 分鐘心率變異度分析，以白檀香 10 滴、羅勒 10 滴、絲 柏 10 滴、迷迭香 10 滴、薄荷 10 滴、快樂鼠尾草 10 滴精油調和於 100ml 之黃金果油中，進 行滾珠瓶調油刮痧與擴香吸嗅，之後再做心率變異度分析後測 3 分鐘。透過心率變異前後測 的心率變異數值來評估改善差異。最後以 Excel 做分析、統計，讓本研究更具有信效度。
關鍵詞：頭皮紓壓、精油滾珠瓶、芳香保健按摩、心律變異儀
Abstract
According to the statistics of the Bureau of Labor Insurance, the incidence of musculoskeletal pain increased from 58% in 2000 to 85% in 2010 (the Institute of Labor Safety and Health of the Labor Council, 2014). Foreign surveys found that the chronic pain rate of the elderly in institutions was 48.5~ 79% (Won et al., 2004), the chronic pain rate among Taiwanese elderly is 42% in the community, and 43.1-65.3% in institutions (Tsarist al., 2004; Tsai et al., 2005), among which scalp, arthritis The pain, stiffness and swelling caused by it is the main cause of long-term chronic pain in many elderly people, which often affects joints such as head, knee, hip, shoulder and fingers (Lansbury, 2000). When the hand or arm joint is sore, it will cause movement function Restricted and unable to perform daily life (Miller & Reynolds, 2012), it is very important to deal with the scalp pressure and soreness of the elderly. Aromatic essential oils are mainly plants that convert the nutrients produced by their own photosynthesis into aromatic molecules and then use essential oils to extract the essence of plants. It is the most precious gift from nature to human beings. Use essential oils and natural plant essence roller ball bottles to promote physical and mental health, through the skin, meridians to the nervous system, hormonal system, blood system, immune system, to help the body and mind relax, regulate metabolism, and achieve the function of promoting physical health and psychological pleasure. Solve the scalp, muscle and health problems of silver-haired people caused by internal emotional disorders caused by work life and life pressure. The purpose of this study is to use essential oils such as white sandalwood, basil, cypress, rosemary, clary sage, and bergamot together with sweet almond oil for roller-ball bottle and scraping massage. A similar experiment method is adopted, and random sampling is adopted. The samples are from Keelung 12 There are people aged 50 to 65, mainly silver-haired people who work. The objects are medical staff, teaching staff, and the elderly in general. It is expected to do scalp aroma relief and aromatherapy inhalation. For eight weeks, the aroma oil roller ball bottle will be involved in scraping massage to improve the protection of daily life and environmental immunity. Before the experiment, the subjects were subjected to heart rate variability analysis for 3 minutes, and mixed with 100ml essential oils of white sandalwood, 10 drops of basil, 10 drops of cypress, 10 drops of rosemary, 10 drops of mint, and 10 drops of clary sage. In the golden fruit oil, perform oil-adjusting scraping in a roller bottle, diffuse fragrance and inhale, and then do heart rate variability analysis and measure for 3 minutes. Finally, Excel was used for analysis and statistics to make this research more reliable and valid.
Key Words：Scalp , Essential Oil Bottle, Aroma Massage, Heart Rate Variation (HRV).
